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What is a Fluid Mosaic

[Summary]Fluid mosaic model Home » Mosaic » Fluid mosaic model A model conceived by S.J. Singer and Garth Nicolson in 1972 to describe the structural features of biological membranes. The plasma membrane is described to be fluid because of its hydrophobic int

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Fluid mosaic model

Home » Mosaic » Fluid mosaic model

A model conceived by S.J. Singer and Garth Nicolson in 1972 to describe the structural features of biological membranes.

The plasma membrane is described to be fluid because of its hydrophobic integral components such as lipids and membrane proteins that move laterally or sideways throughout the membrane. That means the membrane is not solid, but more like a 'fluid'.

Fluid mosaic model | Define Fluid mosaic model at Dictionary.com

fluid mosaic model definition

A model that describes the structure of cell membranes. In this model, a flexible layer made of lipid molecules is interspersed with large protein molecules that act as channels through which other molecules enter and leave the cell.

Fluid mosaic model

Fluid mosaic model of a cell membrane

The fluid mosaic model explains various observations regarding the structure of functional cell membranes. The model, which was devised by SJ Singer and GL Nicolson in 1972, describes the cell membrane as a two-dimensional liquid that restricts the lateral diffusion of membrane components. Such domains are defined by the existence of regions within the membrane with special lipid and protein composition that promote the formation of lipid rafts or protein and glycoprotein complexes. Another way to define membrane domains is the association of the lipid membrane with the cytoskeleton filaments and the extracellular matrix through membrane proteins.[1] The current model describes important features relevant to many cellular processes, including: cell-cell signaling, apoptosis, cell division, membrane budding, and cell fusion.

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