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Addiction vs Tolerance

[Summary]Addiction vs Physical Dependence Physical Dependence In short a physical dependence to opioids means that the body relies on a external source of opioids to prevent withdrawal. Physical dependence is predictable, easily managed with medication, and i

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Addiction vs Physical Dependence

Physical Dependence

In short a physical dependence to opioids means that the body relies on a external source of opioids to prevent withdrawal. Physical dependence is predictable, easily managed with medication, and is ultimately resolved with a slow taper off of the opioid.

Normally, the body is able to produce enough endogenous opioids (example: endorphins) to prevent withdrawal. But as tolerance increases, eventually the body's ability to maintain this equilibrium is exceeded and the body becomes dependent on that external source.

Substance use disorder

Substance use disorder (SUD), also known as drug use disorder, is a condition in which the use of one or more substances leads to a clinically significant impairment or distress.[1] Although the term substance can refer to any physical matter, 'substance' in this context is limited to psychoactive drugs. Addiction and dependence are components of a substance use disorder and addiction represents the most severe form of the disorder.[2][3]

Addiction — Wikipédia

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L'addiction, ou dépendance, est, au sens phénoménologique, une conduite qui repose sur une envie répétée et irrépressible, en dépit de la motivation et des efforts du sujet pour s'y soustraire. Le sujet se livre à son addiction (par exemple : utilisation d'une drogue, ou participation à un jeu d'argent), malgré la conscience aiguë qu'il a — le plus souvent — d'abus et de perte de sa liberté d'action, ou de leur éventualité.

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